HSPMdb Accession NoHSPMDB000468
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound Name9
IUPAC Name(2R,3R,4S,5R)-2-{6-Amino-8-[(quinolin-6-ylmethyl)amino]purin-9-yl}-5-hydroxymethyltetrahydrofuran-3,4-diol
SMILESNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccc5ncccc5c4)nc12
ClassAdenosine derivative
GI50 (µM)>80
Site of InteractionNucleotide binding domain
Cellular assayMTT viability assay
Cellular ModelHCT116

Structure



HSPMDB000468

9

Physicochemical Properties