HSPMdb Accession No | HSPMDB000467 |
PMID | 19256508 |
Target | Hsp70 |
HSP Name | Hsc70 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Antiproliferative activity |
Compound Name | 8 |
IUPAC Name | (2R,3R,4S,5R)-2-{6-Amino-8-[(benzo[1,3]dioxol-5-ylmethyl)-amino]-purin-9-yl}-5- hydroxymethyltetrahydrofuran-3,4-diol |
SMILES | Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccc5OCOc5c4)nc12 |
Class | Adenosine derivative |
GI50 (µM) | >80 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | MTT viability assay |
Cellular Model | HCT116 |