HSPMdb Accession NoHSPMDB000466
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound Name7
IUPAC Name(2R,3R,4S,5R)-2-[6-Amino-8-(3,4-dichlorobenzylamino)purin-9-yl]-5-hydroxymethyltetrahydrofuran-3,4-diol
SMILESNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccc(Cl)c(Cl)c4)nc12
ClassAdenosine derivative
GI50 (µM)26
Site of InteractionNucleotide binding domain
Cellular assayMTT viability assay
Cellular ModelHCT116

Structure



HSPMDB000466

7

Physicochemical Properties