HSPMdb Accession No | HSPMDB000466 |
PMID | 19256508 |
Target | Hsp70 |
HSP Name | Hsc70 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Antiproliferative activity |
Compound Name | 7 |
IUPAC Name | (2R,3R,4S,5R)-2-[6-Amino-8-(3,4-dichlorobenzylamino)purin-9-yl]-5-hydroxymethyltetrahydrofuran-3,4-diol |
SMILES | Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccc(Cl)c(Cl)c4)nc12 |
Class | Adenosine derivative |
GI50 (µM) | 26 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | MTT viability assay |
Cellular Model | HCT116 |