HSPMdb Accession NoHSPMDB000465
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound Name6
IUPAC Name(2R,3R,4S,5R)-2-[6-amino-8-(benzylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
SMILESNC1=C2N=C(NCC3=CC=CC=C3)N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
ClassAdenosine derivative
GI50 (µM)>80
Site of InteractionNucleotide binding domain
Cellular assayMTT viability assay
Cellular ModelHCT116

Structure



HSPMDB000465

6

Physicochemical Properties