HSPMdb Accession NoHSPMDB000464
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound Name5
IUPAC Name(2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
SMILESCNC1=NC2=C(N)N=CN=C2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
ClassAdenosine derivative
GI50 (µM)13
Site of InteractionNucleotide binding domain
Cellular assayMTT viability assay
Cellular ModelHCT116

Structure



HSPMDB000464

5

Physicochemical Properties