HSPMdb Accession NoHSPMDB000459
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Enzymatic activityBinding affinity
Compound Name14
IUPAC Name(2R,3R,4S,5R)-2-[6-Amino-8-(3,4-dichlorobenzylamino)-purin-9-yl]-5-(3,4,5-trifluorobenzyloxymethyl)-tetrahydrofuran-3,4-diol
SMILESNc1ncnc2n([C@@H]3O[C@H](COCc4cc(F)c(F)c(F)c4)[C@@H](O)[C@H]3O)c(NCc5ccc(Cl)c(Cl)c5)nc12
ClassAdenosine derivative
Kd (µM)4.2
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayHSP70 Biacore Direct Binding Assay

Structure



HSPMDB000459

14

Physicochemical Properties