HSPMdb Accession NoHSPMDB000458
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Enzymatic activityBinding affinity
Compound Name13
IUPAC Name4-[(2R,3S,4R,5R)-5-(6-Amino-8-benzylamino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2- ylmethoxymethyl]-benzonitrile
SMILESNc1ncnc2n([C@@H]3O[C@H](COCc4ccc(cc4)C#N)[C@@H](O)[C@H]3O)c(NCc5ccccc5)nc12
ClassAdenosine derivative
Kd (µM)0.2
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayHSP70 Biacore Direct Binding Assay

Structure



HSPMDB000458

13

Physicochemical Properties