HSPMdb Accession NoHSPMDB000448
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATP binding
Compound Name11
IUPAC Name(2R,3R,4S,5R)-2-[6-Amino-8-(3,4-dichlorobenzylamino)-purin-9-yl]-5-benzyloxymethyltetrahydrofuran-3,4-diol
SMILESNc1ncnc2n([C@@H]3O[C@H](COCc4ccccc4)[C@@H](O)[C@H]3O)c(NCc5ccc(Cl)c(Cl)c5)nc12
ClassAdenosine derivative
IC50 (µM)2.4
Site of InteractionNucleotide binding domain
Type of Enzymatic Assay Fluorescence polarization (FP) assay

Structure



HSPMDB000448

11

Physicochemical Properties