HSPMdb Accession NoHSPMDB000447
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATP binding
Compound Name10
IUPAC Name(2R,3R,4S,5R)-2-[6-Amino-8-(3,4-dichlorobenzylamino)-purin-9-yl]-5-methoxymethyltetrahydrofuran-3,4-diol
SMILESCOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2c(NCc3ccc(Cl)c(Cl)c3)nc4c(N)ncnc24
ClassAdenosine derivative
IC50 (µM)3.2
Site of InteractionNucleotide binding domain
Type of Enzymatic Assay Fluorescence polarization (FP) assay

Structure



HSPMDB000447

10

Physicochemical Properties