HSPMdb Accession NoHSPMDB000446
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATP binding
Compound Name9
IUPAC Name(2R,3R,4S,5R)-2-{6-Amino-8-[(quinolin-6-ylmethyl)amino]purin-9-yl}-5-hydroxymethyltetrahydrofuran-3,4-diol
SMILESNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc4ccc5ncccc5c4)nc12
ClassAdenosine derivative
IC50 (µM)2.9
Site of InteractionNucleotide binding domain
Type of Enzymatic Assay Fluorescence polarization (FP) assay

Structure



HSPMDB000446

9

Physicochemical Properties