HSPMdb Accession NoHSPMDB000438
PMID19256508
TargetHsp70
HSP NameHsc70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATP binding
Compound Name1
IUPAC Name[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
SMILESC1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
ClassAdenosine derivative
IC50 (µM)0.5
Site of InteractionNucleotide binding domain
Type of Enzymatic Assay Fluorescence polarization (FP) assay

Structure



HSPMDB000438

1

Physicochemical Properties