HSPMdb Accession NoHSPMDB000433
PMID25772468
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound Name15
IUPAC Name4-({2-[3-(difluoromethyl)-5-(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl}methyl)benzamide
SMILESCOC1=CC=C(C=C1)C1=C(N(CC2=CC=C(C=C2)C(N)=O)C(=N1)C1=CC(=CC(=C1)C(F)(F)F)C(F)F)C1=CC=C(OC)C=C1
ClassImidazole library
% Enzymatic Inhibition/Fold Change15% at 100 uM
Type of Enzymatic AssayATPase assay
DiseaseCancer

Structure



HSPMDB000433

15

Physicochemical Properties