HSPMdb Accession No | HSPMDB000428 |
PMID | 25772468 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 10 |
IUPAC Name | N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-({2-[3-(difluoromethyl)-5-(trifluoromethyl)phenyl]-4,5-bis(4-methylphenyl)-1H-imidazol-1-yl}methyl)benzamide |
SMILES | CC1=CC=C(C=C1)C1=C(N(CC2=CC=C(C=C2)C(=O)NCCOCCOCCN)C(=N1)C1=CC(=CC(=C1)C(F)(F)F)C(F)F)C1=CC=C(C)C=C1 |
Class | Imidazole library |
% Enzymatic Inhibition/Fold Change | 12.5% at 100 uM |
Type of Enzymatic Assay | ATPase assay |
Disease | Cancer |