HSPMdb Accession NoHSPMDB000428
PMID25772468
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound Name10
IUPAC NameN-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-({2-[3-(difluoromethyl)-5-(trifluoromethyl)phenyl]-4,5-bis(4-methylphenyl)-1H-imidazol-1-yl}methyl)benzamide
SMILESCC1=CC=C(C=C1)C1=C(N(CC2=CC=C(C=C2)C(=O)NCCOCCOCCN)C(=N1)C1=CC(=CC(=C1)C(F)(F)F)C(F)F)C1=CC=C(C)C=C1
ClassImidazole library
% Enzymatic Inhibition/Fold Change12.5% at 100 uM
Type of Enzymatic AssayATPase assay
DiseaseCancer

Structure



HSPMDB000428

10

Physicochemical Properties