HSPMdb Accession No | HSPMDB000427 |
PMID | 25772468 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 9 |
IUPAC Name | N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-{[4,5-bis(4-bromophenyl)-2-[3-(difluoromethyl)-5-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]methyl}benzamide |
SMILES | NCCOCCOCCNC(=O)C1=CC=C(CN2C(=NC(=C2C2=CC=C(Br)C=C2)C2=CC=C(Br)C=C2)C2=CC(=CC(=C2)C(F)(F)F)C(F)F)C=C1 |
Class | Imidazole library |
% Enzymatic Inhibition/Fold Change | 10% at 100 uM |
Type of Enzymatic Assay | ATPase assay |
Disease | Cancer |