HSPMdb Accession NoHSPMDB000426
PMID25772468
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound Name8
IUPAC NameN-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-{[4,5-bis(4-chlorophenyl)-2-[3-(difluoromethyl)-5-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]methyl}benzamide
SMILESNCCOCCOCCNC(=O)C1=CC=C(CN2C(=NC(=C2C2=CC=C(Cl)C=C2)C2=CC=C(Cl)C=C2)C2=CC(=CC(=C2)C(F)(F)F)C(F)F)C=C1
ClassImidazole library
% Enzymatic Inhibition/Fold Change7.5% at 100 uM
Type of Enzymatic AssayATPase assay
DiseaseCancer

Structure



HSPMDB000426

8

Physicochemical Properties