HSPMdb Accession NoHSPMDB000424
PMID25772468
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound Name6
IUPAC NameN-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-{[2-(3,5-dimethoxyphenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl]methyl}benzamide
SMILESCOC1=CC=C(C=C1)C1=C(N(CC2=CC=C(C=C2)C(=O)NCCOCCOCCN)C(=N1)C1=CC(OC)=CC(OC)=C1)C1=CC=C(OC)C=C1
ClassImidazole library
% Enzymatic Inhibition/Fold Change10% at 100 uM
Type of Enzymatic AssayATPase assay
DiseaseCancer

Structure



HSPMDB000424

6

Physicochemical Properties