HSPMdb Accession No | HSPMDB000422 |
PMID | 25772468 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 4 |
IUPAC Name | 1,3-dimethyl 5-(1-{[4-({2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}-4,5-bis(4-methoxyphenyl)-1H-imidazol-2-yl)benzene-1,3-dicarboxylate |
SMILES | COC(=O)C1=CC(=CC(=C1)C(=O)OC)C1=NC(=C(N1CC1=CC=C(C=C1)C(=O)NCCOCCOCCN)C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |
Class | Imidazole library |
% Enzymatic Inhibition/Fold Change | 17.5% at 100 uM |
Type of Enzymatic Assay | ATPase assay |
Disease | Cancer |