HSPMdb Accession NoHSPMDB000422
PMID25772468
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound Name4
IUPAC Name1,3-dimethyl 5-(1-{[4-({2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}-4,5-bis(4-methoxyphenyl)-1H-imidazol-2-yl)benzene-1,3-dicarboxylate
SMILESCOC(=O)C1=CC(=CC(=C1)C(=O)OC)C1=NC(=C(N1CC1=CC=C(C=C1)C(=O)NCCOCCOCCN)C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
ClassImidazole library
% Enzymatic Inhibition/Fold Change17.5% at 100 uM
Type of Enzymatic AssayATPase assay
DiseaseCancer

Structure



HSPMDB000422

4

Physicochemical Properties