HSPMdb Accession NoHSPMDB000420
PMID25772468
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound Name2
IUPAC NameN-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-{[4,5-bis(4-methoxyphenyl)-2-[3-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]methyl}benzamide
SMILESCOC1=CC=C(C=C1)C1=C(N(CC2=CC=C(C=C2)C(=O)NCCOCCOCCN)C(=N1)C1=CC=CC(=C1)C(F)(F)F)C1=CC=C(OC)C=C1
ClassImidazole library
% Enzymatic Inhibition/Fold Change12.5% at 100 uM
Type of Enzymatic AssayATPase assay
DiseaseCancer

Structure



HSPMDB000420

2

Physicochemical Properties