HSPMdb Accession NoHSPMDB000419
PMID25772468
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound Name1
IUPAC NameN-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-({2-[2,4-bis(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl}methyl)benzamide
SMILESCOC1=CC=C(C=C1)C1=C(N(CC2=CC=C(C=C2)C(=O)NCCOCCOCCN)C(=N1)C1=C(C=C(C=C1)C(F)(F)F)C(F)(F)F)C1=CC=C(OC)C=C1
ClassImidazole library
% Enzymatic Inhibition/Fold Change17.5% at 100 uM
Type of Enzymatic AssayATPase assay
DiseaseCancer

Structure



HSPMDB000419

1

Physicochemical Properties