HSPMdb Accession NoHSPMDB000410
PMID21338918
TargetHsp70
HSP NameDnaK/ DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound NameHieracin
IUPAC Name5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
SMILESOC1=CC2=C(C(O)=C1)C(=O)C=C(O2)C1=CC(O)=C(O)C(O)=C1
Class Flavonoid
% Enzymatic Inhibition/Fold Change48% at 200 uM
IC50 (µM)28.2
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000410

Hieracin

Physicochemical Properties