HSPMdb Accession NoHSPMDB000366
PMID21426241
TargetHsp70
HSP NamePfHsp70-1
Organism Plasmodium falciparum
LocalizationCytosol and nucleus
Enzymatic activityInhibition of protein aggregation activity
Compound NameMalonganenone C
IUPAC NameN-[(2E,6E,11Z)-3,7,11,15-tetramethyl-13-oxohexadeca-2,6,11-trien-1-yl]formamide
SMILES[H]C(=O)NC\C=C(/C)CC\C=C(/C)CCC\C(C)=C/C(=O)CC(C)C
Class Marine tetraprenylated alkaloid
% Enzymatic Inhibition/Fold Change>90% at 300 uM
Type of Enzymatic Assay Substrate aggregation suppression assay
DiseaseMalaria

Structure



HSPMDB000366

Malonganenone C

Physicochemical Properties