HSPMdb Accession NoHSPMDB000360
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameMAL3-51
IUPAC NameN-[4-[[2-(tert-butylamino)-1-(4-iodophenyl)-2-oxoethyl]-(2-morpholin-4-ylethyl)amino]-4-oxobutyl]benzamide
SMILESCC(C)(C)NC(=O)C(N(CCN1CCOCC1)C(=O)CCCNC(=O)c2ccccc2)c3ccc(I)cc3
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelHT29
DiseaseCancer

Structure



HSPMDB000360

MAL3-51

Physicochemical Properties