HSPMdb Accession No | HSPMDB000359 |
PMID | 18164205 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | MAL3-101 |
IUPAC Name | benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate |
SMILES | CCCCCCN(C(C(=O)NCCCC)c1ccc(OCC(=O)OC)c(c1)C(=O)OC)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)c4ccccc4)C(=C2C)C(=O)OCc5ccccc5 |
Class | Dihydropyrimidine derivative |
GI50 (µM) | >50 |
Cellular assay | MTT viability assay |
Cellular Model | HT29 |
Disease | Cancer |