HSPMdb Accession NoHSPMDB000352
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameDMT003020
IUPAC Name5-[2-(butylamino)-1-[hexyl-[6-[4-methyl-2-oxo-5-phenylmethoxycarbonyl-6-(4-phenylphenyl)-1,6-dihydropyrimidin-3-yl]hexanoyl]amino]-2-oxoethyl]-2-(carboxymethoxy)benzoic acid
SMILESCCCCCCN(C(C(=O)NCCCC)c1ccc(OCC(O)=O)c(c1)C(O)=O)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)c4ccccc4)C(=C2C)C(=O)OCc5ccccc5
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000352

DMT003020

Physicochemical Properties