HSPMdb Accession No | HSPMDB000351 |
PMID | 18164205 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | DMT003110 |
IUPAC Name | benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate |
SMILES | CCCCNC(=O)C(N(CCc1c[nH]c2ccccc12)C(=O)CCCCCN3C(=O)NC(c4ccc(cc4)c5ccccc5)C(=C3C)C(=O)OCc6ccccc6)c7ccc(OCC(=O)OC)c(c7)C(=O)OC |
Class | Dihydropyrimidine derivative |
GI50 (µM) | >50 |
Cellular assay | MTT viability assay |
Cellular Model | SK-BR-3 |
Disease | Cancer |