HSPMdb Accession NoHSPMDB000342
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameDMT003058
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-2-oxo-1-pyridin-2-ylethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C(=O)NCCCC)c1ccccn1)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)c4ccccc4)C(=C2C)C(=O)OCc5ccccc5
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000342

DMT003058

Physicochemical Properties