HSPMdb Accession NoHSPMDB000338
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameDMT002222
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-2-oxo-1-(4-phenylphenyl)ethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C(=O)NCCCC)c1ccc(cc1)c2ccccc2)C(=O)CCCCCN3C(=O)NC(c4ccc(cc4)c5ccccc5)C(=C3C)C(=O)OCc6ccccc6
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000338

DMT002222

Physicochemical Properties