HSPMdb Accession No | HSPMDB000338 |
PMID | 18164205 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | DMT002222 |
IUPAC Name | benzyl 3-[6-[[2-(butylamino)-2-oxo-1-(4-phenylphenyl)ethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate |
SMILES | CCCCCCN(C(C(=O)NCCCC)c1ccc(cc1)c2ccccc2)C(=O)CCCCCN3C(=O)NC(c4ccc(cc4)c5ccccc5)C(=C3C)C(=O)OCc6ccccc6 |
Class | Dihydropyrimidine derivative |
GI50 (µM) | >50 |
Cellular assay | MTT viability assay |
Cellular Model | SK-BR-3 |
Disease | Cancer |