HSPMdb Accession No | HSPMDB000334 |
PMID | 18164205 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | DMT003132 |
IUPAC Name | benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-hexylamino]-6-oxohexyl]-6-cyclopropyl-4-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate |
SMILES | CCCCCCN(C(C(=O)NCCCC)c1ccc(OCC(=O)OC)c(c1)C(=O)OC)C(=O)CCCCCN2C(=O)NC(C3CC3)C(=C2C)C(=O)OCc4ccccc4 |
Class | Dihydropyrimidine derivative |
GI50 (µM) | 6.2 |
Cellular assay | MTT viability assay |
Cellular Model | SK-BR-3 |
Disease | Cancer |