HSPMdb Accession NoHSPMDB000332
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameDMT003096
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(2-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C(=O)NCCCC)c1ccc(OCC(=O)OC)c(c1)C(=O)OC)C(=O)CCCCCN2C(=O)NC(c3ccccc3c4ccccc4)C(=C2C)C(=O)OCc5ccccc5
ClassDihydropyrimidine derivative
GI50 (µM)17
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000332

DMT003096

Physicochemical Properties