HSPMdb Accession NoHSPMDB000324
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameDMT003046
IUPAC Namebenzyl 6-cyclopropyl-3-(6-methoxy-6-oxohexyl)-4-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
SMILESCOC(=O)CCCCCN1C(=O)NC(C2CC2)C(=C1C)C(=O)OCc3ccccc3
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000324

DMT003046

Physicochemical Properties