HSPMdb Accession NoHSPMDB000320
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameMAL2-11B
IUPAC Name6-[4-methyl-2-oxo-5-phenylmethoxycarbonyl-6-(4-phenylphenyl)-1,6-dihydropyrimidin-3-yl]hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc(cc2)c3ccccc3)C(=O)OCc4ccccc4
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000320

MAL2-11B

Physicochemical Properties