HSPMdb Accession NoHSPMDB000318
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameMAL2-116-17
IUPAC Name6-[4-methyl-6-(3-nitrophenyl)-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl]hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2cccc(c2)[N+]([O-])=O)C(=O)OCc3ccccc3
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000318

MAL2-116-17

Physicochemical Properties