HSPMdb Accession NoHSPMDB000316
PMID18164205
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NameMAL2-06A
IUPAC Name6-(4-methyl-6-naphthalen-2-yl-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl)hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc3ccccc3c2)C(=O)OCc4ccccc4
ClassDihydropyrimidine derivative
GI50 (µM)>50
Cellular assayMTT viability assay
Cellular ModelSK-BR-3
DiseaseCancer

Structure



HSPMDB000316

MAL2-06A

Physicochemical Properties