HSPMdb Accession No | HSPMDB000316 |
PMID | 18164205 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | MAL2-06A |
IUPAC Name | 6-(4-methyl-6-naphthalen-2-yl-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl)hexanoic acid |
SMILES | CC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc3ccccc3c2)C(=O)OCc4ccccc4 |
Class | Dihydropyrimidine derivative |
GI50 (µM) | >50 |
Cellular assay | MTT viability assay |
Cellular Model | SK-BR-3 |
Disease | Cancer |