HSPMdb Accession No | HSPMDB000315 |
PMID | 18164205 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | MAL1-274 |
IUPAC Name | 6-[6-(4-chlorophenyl)-4-methyl-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl]hexanoic acid |
SMILES | CC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc(Cl)cc2)C(=O)OCc3ccccc3 |
Class | Dihydropyrimidine derivative |
GI50 (µM) | >50 |
Cellular assay | MTT viability assay |
Cellular Model | SK-BR-3 |
Disease | Cancer |