HSPMdb Accession NoHSPMDB000305
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameDMT003110
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCNC(=O)C(N(CCc1c[nH]c2ccccc12)C(=O)CCCCCN3C(=O)NC(c4ccc(cc4)c5ccccc5)C(=C3C)C(=O)OCc6ccccc6)c7ccc(OCC(=O)OC)c(c7)C(=O)OC
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -1.3
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000305

DMT003110

Physicochemical Properties