HSPMdb Accession NoHSPMDB000304
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameDMT003108
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-(2-pyridin-2-ylethyl)amino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCNC(=O)C(N(CCc1ccccn1)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)c4ccccc4)C(=C2C)C(=O)OCc5ccccc5)c6ccc(OCC(=O)OC)c(c6)C(=O)OC
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -1.1
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000304

DMT003108

Physicochemical Properties