HSPMdb Accession NoHSPMDB000293
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameDMT002260
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-(3-methoxycarbonylphenyl)-2-oxoethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C(=O)NCCCC)c1cccc(c1)C(=O)OC)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)c4ccccc4)C(=C2C)C(=O)OCc5ccccc5
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -2.0
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000293

DMT002260

Physicochemical Properties