HSPMdb Accession NoHSPMDB000286
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameDMT003096
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(2-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C(=O)NCCCC)c1ccc(OCC(=O)OC)c(c1)C(=O)OC)C(=O)CCCCCN2C(=O)NC(c3ccccc3c4ccccc4)C(=C2C)C(=O)OCc5ccccc5
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -4.0
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000286

DMT003096

Physicochemical Properties