HSPMdb Accession NoHSPMDB000273
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameMAL2-116-20
IUPAC Name6-[4-methyl-2-oxo-5-phenylmethoxycarbonyl-6-[4-(trifluoromethyl)phenyl]-1,6-dihydropyrimidin-3-yl]hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc(cc2)C(F)(F)F)C(=O)OCc3ccccc3
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 1.1
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000273

MAL2-116-20

Physicochemical Properties