HSPMdb Accession NoHSPMDB000268
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameDMT003116
IUPAC Name6-[6-(4-cyclohexylphenyl)-4-methyl-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl]hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc(cc2)C3CCCCC3)C(=O)OCc4ccccc4
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -2.4
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000268

DMT003116

Physicochemical Properties