HSPMdb Accession NoHSPMDB000266
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameDMT003036
IUPAC Name6-[6-(4-tert-butylphenyl)-4-methyl-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl]hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc(cc2)C(C)(C)C)C(=O)OCc3ccccc3
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -3.5
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000266

DMT003036

Physicochemical Properties