HSPMdb Accession NoHSPMDB000263
PMID18164205
TargetHsp70
HSP NameSsa1p and TAg
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameMAL3-51
IUPAC NameN-[4-[[2-(tert-butylamino)-1-(4-iodophenyl)-2-oxoethyl]-(2-morpholin-4-ylethyl)amino]-4-oxobutyl]benzamide
SMILESCC(C)(C)NC(=O)C(N(CCN1CCOCC1)C(=O)CCCNC(=O)c2ccccc2)c3ccc(I)cc3
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -2.0
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000263

MAL3-51

Physicochemical Properties