HSPMdb Accession NoHSPMDB000255
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameDMT003102
IUPAC Namebenzyl 3-[6-[benzyl-[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]amino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCNC(=O)C(N(Cc1ccccc1)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)c4ccccc4)C(=C2C)C(=O)OCc5ccccc5)c6ccc(OCC(=O)OC)c(c6)C(=O)OC
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 1.5
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000255

DMT003102

Physicochemical Properties