HSPMdb Accession NoHSPMDB000254
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameDMT003052
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-(2-methoxyethyl)amino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCNC(=O)C(N(CCOC)C(=O)CCCCCN1C(=O)NC(c2ccc(cc2)c3ccccc3)C(=C1C)C(=O)OCc4ccccc4)c5ccc(OCC(=O)OC)c(c5)C(=O)OC
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 1.5
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000254

DMT003052

Physicochemical Properties