HSPMdb Accession NoHSPMDB000249
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameDMT002264
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-cyclohexyl-2-oxoethyl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C1CCCCC1)C(=O)NCCCC)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)c4ccccc4)C(=C2C)C(=O)OCc5ccccc5
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 3.2
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000249

DMT002264

Physicochemical Properties