HSPMdb Accession NoHSPMDB000248
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameDMT002262
IUPAC Namebenzyl 3-[6-[[1-(butylamino)-1-oxopropan-2-yl]-hexylamino]-6-oxohexyl]-4-methyl-2-oxo-6-(4-phenylphenyl)-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C)C(=O)NCCCC)C(=O)CCCCCN1C(=O)NC(c2ccc(cc2)c3ccccc3)C(=C1C)C(=O)OCc4ccccc4
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 1.6
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000248

DMT002262

Physicochemical Properties