HSPMdb Accession NoHSPMDB000241
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameDMT003100
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-hexylamino]-6-oxohexyl]-6-cyclohexyl-4-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C(=O)NCCCC)c1ccc(OCC(=O)OC)c(c1)C(=O)OC)C(=O)CCCCCN2C(=O)NC(C3CCCCC3)C(=C2C)C(=O)OCc4ccccc4
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 1.2
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000241

DMT003100

Physicochemical Properties