HSPMdb Accession NoHSPMDB000234
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameDMT003084
IUPAC Namebenzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]-hexylamino]-6-oxohexyl]-6-(4-tert-butylphenyl)-4-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
SMILESCCCCCCN(C(C(=O)NCCCC)c1ccc(OCC(=O)OC)c(c1)C(=O)OC)C(=O)CCCCCN2C(=O)NC(c3ccc(cc3)C(C)(C)C)C(=C2C)C(=O)OCc4ccccc4
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 1.2
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000234

DMT003084

Physicochemical Properties