HSPMdb Accession NoHSPMDB000224
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameMAL2-06A
IUPAC Name6-(4-methyl-6-naphthalen-2-yl-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl)hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc3ccccc3c2)C(=O)OCc4ccccc4
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -1.1
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000224

MAL2-06A

Physicochemical Properties