HSPMdb Accession NoHSPMDB000223
PMID18164205
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound NameMAL1-274
IUPAC Name6-[6-(4-chlorophenyl)-4-methyl-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl]hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)c2ccc(Cl)cc2)C(=O)OCc3ccccc3
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change 1.3
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000223

MAL1-274

Physicochemical Properties